| 1 |
Asan Medical Center Seoul, South Korea · 9 spellings merged |
13 11 completed, 2 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
|
2026-01-28 |
8 |
90 |
| 2 |
Samsung Medical Center Seoul, South Korea · 7 spellings merged |
13 10 completed, 3 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
|
2026-01-28 |
12 |
87 |
| 3 |
Seoul National University Hospital Seoul, South Korea · 6 spellings merged |
13 10 completed, 3 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
|
2026-01-28 |
9 |
87 |
| 4 |
Severance Hospital, Yonsei University Health System Seoul, South Korea · 11 spellings merged |
13 11 completed, 2 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
|
2026-01-28 |
10 |
92 |
| 5 |
University of Oklahoma Health Sciences Center Oklahoma City, United States · 11 spellings merged |
13 10 completed, 3 terminated |
6 trials with titles- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
- NCT03476798 Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium completed 2023-09-29
- NCT02635360 Pembrolizumab and Chemoradiation Treatment for Advanced Cervical Cancer completed 2022-12-14
- NCT03438396 A Trial of Tisotumab Vedotin in Cervical Cancer completed 2022-08-02
|
2025-08-22 |
10 |
88 |
| 6 |
MD Anderson Cancer Center Houston, United States · 9 spellings merged |
12 7 completed, 5 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT05572684 A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors terminated 2025-04-30
Stop reason on the record: “Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.” - NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
- NCT05500508 Oral AMXT 1501 Dicaprate in Combination With IV DFMO terminated 2024-12-12
Stop reason on the record: “Required re-formulation of DFMO from IV to capsule to maintain safety” - NCT05012397 Milademetan in Advanced/Metastatic Solid Tumors terminated 2023-10-15
Stop reason on the record: “Sponsor Decision”
|
2026-01-28 |
15 |
83 |
| 7 |
Cliniques Universitaires Saint-Luc Brussels, Belgium · 6 spellings merged |
11 9 completed, 2 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT04405349 Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer completed 2023-11-24
- NCT03257267 Study of Cemiplimab in Adults With Cervical Cancer completed 2023-04-20
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
|
2026-03-19 |
4 |
81 |
| 8 |
Gustave Roussy Villejuif, France · 10 spellings merged |
11 8 completed, 3 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT03612791 Trial Assessing the Inhibitor of Programmed Cell Death Ligand 1 (PD-L1) Immune Checkpoint Atezolizumab completed 2025-05-13
|
2026-01-28 |
11 |
93 |
| 9 |
Dana-Farber Cancer Institute Boston, United States · 3 spellings merged |
10 6 completed, 4 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
- NCT05012397 Milademetan in Advanced/Metastatic Solid Tumors terminated 2023-10-15
Stop reason on the record: “Sponsor Decision” - NCT02865135 Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer completed 2023-02-06
- NCT04171700 A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes terminated 2022-07-15
Stop reason on the record: “The study was terminated due to a change in development priorities.”
|
2026-03-19 |
12 |
86 |
| 10 |
Augusta University Augusta, United States · 6 spellings merged |
9 7 completed, 2 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
- NCT04380805 A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer completed 2023-01-31
|
2026-03-19 |
5 |
83 |
| 11 |
Universitair Ziekenhuis Gent Ghent, Belgium · 7 spellings merged |
9 6 completed, 3 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT04646005 Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy completed 2024-05-29
- NCT04405349 Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer completed 2023-11-24
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
|
2026-03-19 |
5 |
78 |
| 12 |
Sun Yat-sen University Cancer Center Guangzhou, China · 8 spellings merged |
9 5 completed, 4 terminated |
6 trials with titles- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT06022757 Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19) terminated 2025-01-13
Stop reason on the record: “Strategic decision by Sponsor.” - NCT05179239 A Study of SHR-1701 Plus Platinum-containing Chemotherapy With or Without BP102 (Bevacizumab) as First-line Treatment in Cervical Cancer terminated 2024-08-12
Stop reason on the record: “Sponsor develops strategy adjustment” - NCT04799639 Efficacy and Toxicity of Paclitaxel, Cisplatin Combined With Sindilimab in NACT for Locally Advanced Cervical Cancer completed 2024-06-24
- NCT04341883 Study of Anti-PD-1 Combined With Albumin-Bound Paclitaxel in Patients With Recurrent Cervical Cancer completed 2024-04-26
- NCT04974944 First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in Advanced Cervical Cancer terminated 2024-01-08
Stop reason on the record: “No superior PFS in study group among the enrolled patients. Company R\&D strategy shifted; funding discontinued, study terminated.”
|
2026-01-15 |
12 |
89 |
| 13 |
Centre Léon Bérard Lyon, France · 3 spellings merged |
9 8 completed, 1 terminated |
6 trials with titles- NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT04357873 Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations completed 2024-11-26
- NCT03946358 Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL) completed 2024-11-01
|
2025-08-31 |
9 |
97 |
| 14 |
Istituto Europeo di Oncologia Milan, Italy · 10 spellings merged |
8 7 completed, 1 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
|
2026-03-19 |
5 |
94 |
| 15 |
Karmanos Cancer Institute Detroit, United States · 5 spellings merged |
8 7 completed, 1 terminated |
6 trials with titles- NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
- NCT03989115 Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC completed 2022-02-08
- NCT03602079 Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene completed 2022-01-12
|
2026-01-26 |
5 |
93 |
| 16 |
Moffitt Cancer Center Tampa, United States · 7 spellings merged |
8 5 completed, 3 terminated |
6 trials with titles- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT03674567 Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab completed 2024-12-31
- NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
- NCT04171700 A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes terminated 2022-07-15
Stop reason on the record: “The study was terminated due to a change in development priorities.” - NCT03989115 Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC completed 2022-02-08
|
2025-08-22 |
8 |
86 |
| 17 |
National Institutes of Health Clinical Center Bethesda, United States · 3 spellings merged |
7 6 completed, 1 terminated |
6 trials with titles- NCT04708470 A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers completed 2026-08-21
- NCT04287868 Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies completed 2026-05-14
- NCT04432597 HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers completed 2026-03-31
- NCT02858310 E7 TCR T Cells for Human Papillomavirus-Associated Cancers completed 2025-07-02
- NCT06865677 Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas terminated 2025-07-01
Stop reason on the record: “This protocol was terminated prematurely because the prior principal investigator departed the Institute without treating any participants.” - NCT02487095 Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers completed 2024-12-26
|
2026-08-21 |
3 |
96 |
| 18 |
Hospital Universitari Vall d'Hebron Barcelona, Spain · 9 spellings merged |
7 5 completed, 2 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT04646005 Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy completed 2024-05-29
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
|
2026-03-19 |
6 |
87 |
| 19 |
Hospital Universitario 12 de Octubre Madrid, Spain · 6 spellings merged |
7 6 completed, 1 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
- NCT03438396 A Trial of Tisotumab Vedotin in Cervical Cancer completed 2022-08-02
|
2026-03-19 |
7 |
84 |
| 20 |
Memorial Sloan Kettering Cancer Center New York, United States · 5 spellings merged |
7 5 completed, 2 terminated |
6 trials with titles- NCT03786081 Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer terminated 2026-03-19
Stop reason on the record: “Sponsor has decided to stop the trial based on strategic decisions” - NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT05012397 Milademetan in Advanced/Metastatic Solid Tumors terminated 2023-10-15
Stop reason on the record: “Sponsor Decision” - NCT03989115 Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC completed 2022-02-08
- NCT03126110 Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies completed 2021-11-09
- NCT03180294 Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer completed 2021-02-22
|
2026-03-19 |
6 |
81 |
| 21 |
Centre Oscar Lambret Lille, France · 4 spellings merged |
7 5 completed, 2 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT03556839 Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix completed 2025-08-31
- NCT04016142 Carboplatin-Paclitaxel Adjuvant Chemotherapy in the Treatment of Locally Advanced Cervical Cancer terminated 2025-01-31
Stop reason on the record: “The study is discontinued because of recruitment failure, and for strategic reason (competitive trials with immunotherapy)” - NCT04357873 Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations completed 2024-11-26
- NCT04205799 Cabozantinib for Advanced or Metastatic Cervical Carcinoma After Platinum Treatment Failure completed 2023-01-15
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
|
2026-01-28 |
4 |
91 |
| 22 |
Princess Margaret Cancer Centre Toronto, Canada · 6 spellings merged |
7 6 completed, 1 terminated |
6 trials with titles- NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression terminated 2026-01-28
Stop reason on the record: “Sponsor Decision” - NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT03635567 Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) completed 2024-06-04
- NCT03257267 Study of Cemiplimab in Adults With Cervical Cancer completed 2023-04-20
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2026-01-28 |
8 |
90 |
| 23 |
Chongqing Cancer Hospital Chongqing, China · 5 spellings merged |
7 7 completed, 0 terminated |
6 trials with titles- NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05383482 Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1 completed 2024-07-18
- NCT04870177 Study of AK112 in the Treatment of Advanced Gynecological Tumors completed 2024-05-10
- NCT04693234 AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer completed 2023-08-31
- NCT04246489 Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer completed 2022-12-14
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2026-01-26 |
7 |
94 |
| 24 |
Mackay Memorial Hospital Taipei, Taiwan · 7 spellings merged |
7 6 completed, 1 terminated |
6 trials with titles- NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT04697628 Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer completed 2026-01-15
- NCT05007106 MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) completed 2025-08-05
- NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer completed 2025-02-24
- NCT04693234 AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer completed 2023-08-31
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2026-01-26 |
2 |
85 |
| 25 |
Ohio State University Comprehensive Cancer Center Columbus, United States · 12 spellings merged |
7 4 completed, 3 terminated |
6 trials with titles- NCT04221945 Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047) completed 2026-01-26
- NCT03108495 Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma terminated 2025-08-22
Stop reason on the record: “After reviewing available safety and efficacy data to date, Iovance concluded the study reached the required number of events for evaluation of study endpoints.” - NCT03894215 RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer terminated 2025-03-26
Stop reason on the record: “Sponsor strategic decision” - NCT04171700 A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes terminated 2022-07-15
Stop reason on the record: “The study was terminated due to a change in development priorities.” - NCT03104699 A Study of AGEN2034 in Advanced Tumors and Cervical Cancer completed 2022-06-15
- NCT03989115 Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC completed 2022-02-08
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2026-01-26 |
11 |
85 |